The third video released of the “RNA Explained Series”, is on the genome editing technology, based on the CRISPR/Cas 9 technology, and the Nobel Prize awarded for its development.
Imagine being able to cure genetic diseases by simply rewriting the code of life. For decades, precisely and efficiently changing the letters of our DNA remained just a dream for molecular biologists.
Then came a breakthrough that made the previously unthinkable possible: CRISPR/Cas9. First discovered in bacteria as an immune defense, scientists realized in 2012 that this system could be used to edit any DNA sequence with unprecedented precision.
But how does it work? The central protein, Cas9, acts like molecular scissors. It is directed to the exact right spot in the genome by a short piece of "guide RNA." Once there, Cas9 makes a precise cut, allowing scientists to disrupt faulty genes or even insert new, corrected DNA sequences during the cell's repair process.
This powerful tool promises to transform biomedical science, offering new treatments for genetic disorders, better crops, and innovative medicines.
English subtitles are available on YouTube.